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为探讨单纯急性戊肝AFP含量变化及临床意义,动态检测血清AFP及与ALT,TBIL,白蛋白值的关系。结果表明:戊肝发病年龄高,黄疸重,P<0.05。8/20例戊肝血清AFP含量升高,范围在56.1~494.5μg/L,高峰较ALT,TBIL高峰延迟约一周,肝功恢复2周后基本恢复正常,同期甲肝20例无升高,P<0.05。认为急性单纯戊肝病例可存在一过性AFP升高,推测与戊肝较严重的肝细胞损伤及再生有关。应与肝癌、肝硬化鉴别。
In order to investigate the change of AFP content in acute hepatitis A and its clinical significance, the relationship between serum AFP and ALT, TBIL and albumin values was dynamically detected. The results showed that the incidence of hepatitis E was high and the jaundice was severe. The serum AFP level increased from 56.1 to 494.5 μg / L in P <0.05 and in 20/50 patients, the peak was delayed by about One week, liver function returned to normal after 2 weeks of recovery, 20 cases of HAV did not increase in the same period (P <0.05). Acute simple hepatitis E cases that there may be a transient increase in AFP, presumed to be more serious hepatitis E liver cell injury and regeneration related. Should be identified with liver cancer, cirrhosis.