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目的 探讨乳腺DCIS(ductal carcinoma in situ)的发病趋势及治疗模式的变化.方法 以1982～1995年诊治的479例乳腺DCIS病人为研究对象,进行回顾性分析研究.结果 乳腺DCIS占全部乳腺癌的比例由1982年的3.3%上升到1995年的17.35%,这种趋势发生在40岁以上的各年龄组中,上升最明显的年龄组是40～49岁.乳腺DCIS的治疗模式中,乳腺切除术由100%降至21.95%,局部切除术辅以放射治疗或者单纯局部切除术由0上升至78.05%.结论 近二十年来,乳腺DCIS的发病较前明显增多,其发病年龄趋于年轻化.乳腺DCIS的常用治疗方法是保守手术辅以术后放射治疗.
Objective To investigate the trend of the incidence of ductal carcinoma in situ (DCIS) and the changes of the treatment model. Methods 479 cases of breast DCIS who were diagnosed and treated from 1982 to 1995 were studied retrospectively. The results showed that breast DCIS accounted for all breast cancers. The proportion increased from 3.3% in 1982 to 17.35% in 1995. This trend occurred in age groups above 40 years old. The most obvious age group was 40 to 49 years old. Mammary gland resection was used in the treatment of breast DCIS. The rate of surgery decreased from 100% to 21.95%, and local resection combined with radiation therapy or simple local resection increased from 0 to 78.05%. Conclusions In the past two decades, the incidence of breast DCIS has increased significantly compared with the previous, and its age of onset tends to be younger. The common treatment for breast DCIS is conservative surgery supplemented with postoperative radiotherapy.