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测定３２例受试者２４ｈ食管ｐＨ节律变化，证实胃食管反流病患者与对照组比较，酸反流得分及其他酸反流指标均有明显不同。５例仪有食管反流症状，胃镜检查无食管炎的患者，经食管ｐＨ检测酸反流得分异常，确诊为胃食管反流病。提示食管ｐＨ监测对诊断胃食管反流病具敏感性高和特异性强的优点。不同年龄健康人胃ｐＨ测定表明，青、老年人中位ｐＨ值、基线ｐＨ值、ｐＨ＜２的百分比时间均无明显不同。老年人餐后下降期时间、进餐峰值期ｐＨ较青年人延长。十二指肠球部溃疡患者胃内ｐＨ节律变化与健康人比较有明显不同，其突出特点是中位ｐＨ值低，ｐＨ＜２的百分比时间明显增高，夜间胃内ｐＨ值明显较健康人低，提示２４ｈ胃ｐＨ测定对了解胃酸生理性分泌和胃内酸度可提供客观依据。
Determination of 32 subjects 24h esophageal pH rhythm changes, confirmed that patients with gastroesophageal reflux disease compared with the control group, acid reflux score and other acid reflux indicators were significantly different. Five patients had symptoms of esophageal reflux, gastroscopy without esophagitis in patients with esophageal pH to detect acid reflux score abnormalities, diagnosed with gastroesophageal reflux disease. Tip esophageal pH monitoring for the diagnosis of gastroesophageal reflux disease with high sensitivity and specificity advantages. The gastric pH of healthy people at different ages showed that there was no significant difference in the median pH, the baseline pH and the percentage of pH <2 between the young and the elderly. Elderly postprandial descent period, meal peak pH than young people to extend. Gastric pH rhythms in patients with duodenal ulcer were significantly different from those in healthy subjects, with prominent features of low median pH, a significant increase in the percentage of pH <2, and significantly lower intragastric pH at night than in healthy subjects , Suggesting 24h gastric pH measurement to understand the physiological acid secretion and gastric acidity can provide an objective basis.