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背景:胃癌患者的生活质量受诸多因素的影响,采用线性结构方程式模型,可以揭示不能通过直接观测得到的潜在因子之间的关系,适合对胃癌患者生活质量的影响因素作分析。目的:分析影响长乐县胃癌患者生活质量的因素,为改善农村胃癌患者在生活质量提供科学信息。设计:以诊断为依据的回顾性研究。地点和对象:423例居住在长乐县且由县级以上医院确诊的胃癌患者,其中男355例,女68例;生存时间0.5～15.6年。方法:采用观测性研究方法,每例胃癌患者填写调查表。调查胃癌患者基本情况指标7项,治疗情况25项,生活质量18项。采用因子分析方法对26个变量和18个条目评分进行分析,用线性结构方程式(LISREL)分析潜在外生变量ζ与潜在内生变量η之间的关系。主要观察指标:反映胃癌患者生活质量的18个条目的评分及相关因素的量化值。结果:从反映胃癌患者生活质量的18个条目的评分提取出2个潜在的内生变量,从与生活质量相关的26个显在变量中提取出11个潜在外生变量,二者之间的线性结构方程的拟合优度指数为0.95。结论:胃癌患者的心理状态受到其生理状态的显著影响;影响胃癌患者生活质量的因素有病情、生存时间、年龄、手术情况、性别和营养。
BACKGROUND: The quality of life of patients with gastric cancer is influenced by many factors. Using the linear structural equation model, the relationship between potential factors that can not be directly observed can be revealed and the factors affecting the quality of life of patients with gastric cancer are analyzed. Objective: To analyze the factors that affect the quality of life of patients with gastric cancer in Changle County and provide scientific information for improving quality of life of rural patients with gastric cancer. Design: A retrospective study based on diagnosis. Location and Subjects: There were 423 gastric cancer patients living in Changle County and diagnosed by hospitals at or above the county level, including 355 males and 68 females, with a survival time of 0.5 to 15.6 years. Methods: Observational research methods, each case of gastric cancer patients fill out the questionnaire. Investigate the basic situation of patients with gastric cancer indicators 7, 25 cases of treatment, quality of life 18. Factor analysis was used to analyze the scores of 26 variables and 18 items, and the relationship between latent exogenous variable ζ and latent endogenous variable η was analyzed by linear structural equation (LISREL). MAIN OUTCOME MEASURES: Scores of 18 items reflecting the quality of life of patients with gastric cancer and quantified values of related factors. Results: Two potential endogenous variables were extracted from scores of 18 items reflecting the quality of life of patients with gastric cancer, and 11 potential exogenous variables were extracted from 26 significant variables related to quality of life The goodness of fit index for the linear structure equation is 0.95. Conclusion: The psychological status of patients with gastric cancer is significantly affected by their physiological status. The factors that affect the quality of life of patients with gastric cancer are illness, survival time, age, operation status, gender and nutrition.