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目的:探讨尼尔雌醇与米索前列醇在绝经后妇女取环中的疗效。方法:将90例绝经后要求取环妇女随机分成3组:A组术前7天顿服尼尔雌醇片4 mg,术前3 h口服米索前列醇片0.4 mg;B组术前3 h口服米索前列醇片0.4 mg;C组术前7天顿服尼尔雌醇片4 mg。观察三组术中宫颈软化情况、疼痛反应、取环顺利率和药物不良反应。结果:A组术中宫颈扩张情况和取环顺利率均优于B组和C组,无痛率优于C组,有显著差异。结论:尼尔雌醇配伍米索前列醇有协同作用,应用于绝经后取环安全、有效、成功率高。
Objective: To investigate the efficacy of nylestriol and misoprostol in the fetus of postmenopausal women. Methods: 90 cases of postmenopausal women who were asked to take the ring were randomly divided into 3 groups: group A, 4 days before operation, 4 mg of nylestriol tablets, 0.4 mg of misoprostol tablets 3 hours before operation; Group B, 3 h oral misoprostol tablets 0.4 mg; C group 7 days preoperative nalidol tablets 4 mg. Three cases of intraoperative cervical softening, pain response, take the ring smooth rate and adverse drug reactions. Results: The intraoperative cervical dilatation and smoothing rate in group A were better than those in group B and C, and the painless rate was superior to that in group C, with significant difference. Conclusion: Nilestriol with misoprostol has a synergistic effect. It is safe, effective and successful in taking the ring after menopause.