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自从1960年广泛应用IUD以来,对IUD的作用机制进行了大量研究,一般认为IUD可改变人子宫内膜,以致使植入前的胚胎很难在此种内膜中继续生存从而达到避孕目的。如是,则进入子宫内膜前胚胎发育应属正常,进入宫腔的机会也和未置IUD者一样,且胚胎在消失前应在宫腔内存在一段时间。但Noyes等报告1例用Margulies IUD妇女输卵管发现的卵子为原核细胞。另有报道表明65例置IUD妇女经宫颈子宫冲洗液中仅发现1个未受精卵,而未置IUD的36例中发现8个卵子,其
Since IUD was widely used in 1960, a great deal of research has been done on the mechanism of IUD. It is generally believed that IUD can change human endometrium so that preimplantation embryos can hardly survive in this kind of endometrium so as to achieve contraception. If so, before entering the endometrium embryo development should be normal, the opportunity to enter the uterine and IUD are not the same, and the embryo should disappear in the uterine cavity for some time. However, Noyes et al reported 1 case of oviducts found in Margulies IUD women ovarian prokaryotic cells. Another report shows that 65 cases of IUD women through the cervix uterine flushing fluid found only one unfertilized egg, but not placed IUD found in 36 cases of 8 eggs, which