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通过“结合化学分离与原子吸收分光光度法”对Ｃａ￣（２＋）含量测定和离体输卵管肌条收缩记录方法，研究米非司酮（Ｒｕ４８６）对增加假孕（４ｄ）兔输卵管平滑肌收缩频率，而不改变其收缩张力和振幅时与Ｃａ￣（２＋）之间的关系。结果提示：（１）Ｒｕ４８６对输卵管分泌液和组织内Ｃａ￣（２＋）的含量分布无明显影响；（２）Ｒｕ４８６具有降低细胞外液高Ｃａ￣（２＋）浓度促Ｃａ￣（２＋）内流，而使收缩增强的效应，且能协同Ｃａ￣（２＋）通道阻断剂（Ｖｅｒａｐａｉｎｉｌ）抑制细胞外Ｃａ￣（２＋）内流，而致收缩减弱的效应。
To study the effect of mifepristone (Ru486) on increasing contractile frequency of fallopian tube smooth muscle in pregnancy (4 d) by measuring the content of Ca ~ (2+) and contractile recording in vitro tubal muscle strips by “combined with chemical separation and atomic absorption spectrophotometry” , Without changing the relationship between the tension and amplitude of contraction and Ca ~ (2+). The results showed that: (1) Ru486 had no significant effect on the contents of Ca ~ (2+) in the oviduct secretion and tissue; (2) Ru486 had the effect of decreasing the extracellular Ca ~ (2+) , Thereby enhancing the contractile effect and reducing the contractile effect by inhibiting the influx of extracellular Ca ~ (2 +) in coordination with Ca ~ (2+) channel blocker (Verapainil).