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动物白血病模型包括自发白血病,由物理、化学及生物致癌因子诱发的白血病以及在纯系小鼠中传代的细胞移植性白血病。它们在研究白血病和其他恶性肿瘤病因学、发病学和实验治疗以及新抗癌药物的筛选中都发挥了重要的作用,因而受到各国肿瘤学、血液学、免疫学、遗传学、生化和生物物理以及细胞学等工作者的重视。近年来对于肿瘤的病理发生学、肿瘤细胞移植抗元、膜标记、遗传因素、染色体改变以及肿瘤干细胞
Animal leukemia models include idiopathic leukemias, leukemias induced by physical, chemical and biological carcinogens, and cell-transplanted leukemias that are passaged in pure-line mice. They play an important role in the study of the etiology, pathogenesis and experimental treatment of leukemias and other malignancies, as well as the screening of new anti-cancer drugs and are therefore well accepted by oncology, hematology, immunology, genetics, biochemistry and biophysics As well as cytology and other workers attention. In recent years, the pathology of tumors, tumor cell transplantation antigens, membrane markers, genetic factors, chromosome changes and tumor stem cells