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目的:研究分析采用四联疗法治疗幽门螺杆菌阳性十二指肠球部溃疡的临床效果。方法:选取2011年9月至2013年11月在我院接受治疗的80例幽门螺杆菌阳性十二指肠球部溃疡患者,随机分为治疗组和对照组,每组40例。治疗组患者采用四联疗法治疗,对照组患者采用三联疗法治疗,比较两组患者的治疗效果及不良反应发生情况。结果:治疗组患者的治疗效果要优于对照组的治疗效果(P<0.05);治疗组的不良反应发生率5%要低于对照组的不良反应发生率22.5%(P<0.05),具有统计学意义。结论:幽门螺杆菌阳性十二指肠球部溃疡患者实施四联疗法的治疗效果显著,不良反应小,而且提高了幽门螺杆菌的根除率和溃疡的愈合率,值得临床推广和应用。
Objective: To study the clinical effect of quadruple therapy on Helicobacter pylori-positive duodenal ulcer. Methods: Eighty patients with Helicobacter pylori-positive duodenal ulcer treated in our hospital from September 2011 to November 2013 were randomly divided into treatment group and control group, 40 cases in each group. The patients in the treatment group were treated with quadruple therapy, and the patients in the control group were treated with triple therapy. The treatment effect and adverse reactions in both groups were compared. Results: The treatment effect of the treatment group was better than that of the control group (P <0.05). The incidence of adverse reactions in the treatment group was 5% lower than that in the control group (22.5%, P <0.05) Statistical significance. Conclusion: The treatment of Helicobacter pylori-positive duodenal ulcer patients with quadruple therapy has obvious curative effect, small adverse reaction, and improves the cure rate of Helicobacter pylori eradication and ulcer, which is worthy of clinical promotion and application.