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Glycodelin-A是由分泌期的子宫内膜合成并于妊娠早期在子宫内膜腺体中表达的重要的糖蛋白,它的合成受到多种激素的调节。近年来的研究表明glycodelin-A在母胎抗排斥免疫中发挥了重要的作用,并且这种作用跟它的寡糖序列有关。
Glycodelin-A is an important glycoprotein synthesized by secretory endometrium and expressed in endometrial glands during early pregnancy. Its synthesis is regulated by many hormones. Recent studies have shown that glycodelin-A plays an important role in the anti-rejection immunity of the fetus, and this effect is related to its oligosaccharide sequence.