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目的探讨胃溃疡的预后与幽门螺杆菌(Hp)感染的关联。方法观察40例Hp阳性的胃溃疡患者的内窥镜下表现,与根除Hp后的疗效。结果 Hp感染程度不同的3组在内窥镜下表现无统计学差异(P>0.05);经治疗4周,Hp(+++)组总有效率80.0%,Hp(++)组总有效率83.3%。两组间无统计学差异(P>0.05)。Hp(+)组总有效率100%,与前2组相比均有统计学差异(P<0.05);追访6个月,Hp(+++)组复发3例(20.0%),Hp(++)组复发3例((25.0%),Hp(+)组复发0例。前2组复发率无统计学差异(P>0.05),后1组与前两组相比有统计学差异(P<0.05)。结论 Hp感染程度与胃溃疡镜下表现的严重程度无密切联系,但Hp感染程度轻者对治疗的反应好,预后更好。
Objective To investigate the correlation between the prognosis of gastric ulcer and Helicobacter pylori (Hp) infection. Methods 40 cases of Hp-positive gastric ulcer patients under endoscopic performance, and eradication of Hp after the curative effect. Results There was no significant difference in endoscopy between the three groups (P> 0.05). After 4 weeks of treatment, the total effective rate of Hp (+++) group was 80.0% and that of Hp (++) group was Efficiency 83.3%. There was no significant difference between the two groups (P> 0.05). The total effective rate of Hp (+) group was 100%, which was significantly different from that of the former two groups (P <0.05). After 6 months of follow-up, 3 cases (20.0% (++) group, 3 cases (25.0%), and 0 cases in Hp (+) group.The relapse rate in the first two groups had no significant difference (P> 0.05) (P0.05) .Conclusion The severity of Hp infection is not closely related to the severity of microscopic appearance of gastric ulcer, but mild Hp infection has a good response to treatment and better prognosis.