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盐生植物菊芋(Helianthus tuberosus)是一种新型经济作物,特殊生境可能会使其内生真菌产生特殊的次生代谢产物,如结构新颖或活性显著的化合物.为研究这种耐盐植物内生真菌的次生代谢产物以及植物宿主和内生真菌之间可能存在的关系,本实验室从耐盐菊芋块茎中分离纯化出10株内生真菌,对这10株内生真菌进行抗卤虫活性筛选,初步筛选出1株抗卤虫活性良好的菌株Mucor sp.ht-7,规模发酵后通过提取分离技术得到7个化合物,用波谱手段鉴定了7个化合物的结构,对这株内生真菌和宿主次生代谢产物之间的关系进行分析探讨,并对化合物生物活性加以分析.
The halophyte Helianthus tuberosus is a new type of cash crop, and special habitats may produce special secondary metabolites of endophytic fungi, such as novel or highly active compounds. Fungi secondary metabolites and plant hosts and endophytic fungi possible relationship, the laboratory salt-resistant Jerusalem artichoke tubers isolated from 10 endophytic fungi, these 10 endophytic fungi anti-Artemia activity Screening, a preliminary screening of a good anti-Artemia strains Mucor sp.ht-7, after the size of the fermentation by extraction and separation technology to get seven compounds, the spectrum of the seven compounds identified the structure of this strain of endophytic fungi And host secondary metabolites were analyzed and discussed, and biological activity of compounds were analyzed.