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氨硫脲(结核安)系有效抗痨药物之一,在临床上咸认为治疗浸润型肺结核,枝气管淋巴结结核,结核性枝气管炎有一定之疗效。其在试管内抑制结核菌生长之能力,远较链霉素及对氨柳酸钠为强,即使有安息香酸存在,其抑制结核菌之作用,并不因此减低。其有效治疗剂量亦较小,一般文献提出在成人每日约为150—200毫克,在临床上除少数特殊禁忌症外,一般均可广泛应用,其常见之付作用,为消化道反应如食欲不振,恶心呕吐,其次为,肝炎,蛋白尿及皮炎等。(
Thiourea (tuberculosis Ann) Department of effective anti-tuberculosis drugs, clinically salty that the treatment of infiltration of pulmonary tuberculosis, bronchial lymph node tuberculosis, tuberculous bronchitis have a certain effect. Its ability to inhibit tubercle growth in vitro is much stronger than that of streptomycin and sodium salicylate. It does not reduce the effect of TB even if benzoic acid is present. The effective therapeutic dose is also small, the general literature proposed in adults about 150-200 mg daily, with the exception of a small number of special clinical contraindications, the general can be widely used, the common role of pay for the gastrointestinal reactions such as appetite Unsmooth, nausea and vomiting, followed by hepatitis, proteinuria and dermatitis. (