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目的目的以茂名石化医院用药情况为例分析目前不良药品反应(ADR)的发生特点和规律。方法选择茂名石化医院2005年~2015年收集的3279例药品不良反应报告进行回顾性分析,结合报告对目前药物不良反应提出合理的用药建议。结果果药品不良反应涉及18种类药物,抗感染药居首位(20.62%),其中以氟喹诺酮类药物占比最大(4.48%),不良反应主要表现为消化系统损害(46.78%),而主要引发不良反应的给药途径是静脉滴注(69.90%)。结论医院有必要推进开展临床药物监测活动,临床工作中重视ADR,强调合理用药,减少药品不良反应的发生率,保证患者用药安全。
Objective To analyze the characteristics and laws of the current adverse drug reaction (ADR) by taking the medication of Maoming Petrochemical Hospital as an example. Methods A retrospective analysis of 3279 cases of adverse drug reactions collected in Maoming Petrochemical Hospital from 2005 to 2015 was made, and the reasonable recommendations for the current adverse drug reactions were put forward based on the report. Results The adverse reactions of medicines involved 18 kinds of drugs and the anti-infectives were the first (20.62%), of which fluoroquinolones accounted for the largest proportion (4.48%) and adverse reactions were mainly digestive system damage (46.78%), while the main ones The route of administration that caused adverse reactions was intravenous drip (69.90%). Conclusion It is necessary for the hospital to promote clinical drug monitoring activities. ADR should be emphasized in clinical practice, emphasizing rational drug use, reducing the incidence of adverse drug reactions and ensuring the safety of patients.