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内皮素_1(endothelin_1 ,ET_1)是日本Yanagi sawa[1] 等于1988年从培养的猪主动脉内皮细胞分离并提取的多肽 ,是目前所知作用最强、持续时间最久的缩血管物质和促血管平滑肌细胞有丝分裂原。研究发现 ,先心病肺高压患者血浆ET_1水平升
Endothelin_1, endothelin_1, ET_1 is the polypeptide isolated and extracted from cultured aortic endothelial cells by Yanagi Sawa [1] in Japan in 1988, which is the strongest and longest vasoconstrictor Vascular Smooth Muscle Cells Mitogen. The study found that patients with congenital heart disease with elevated plasma levels of ET_1