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1980年8月~1982年8月,我院与国内23所医院及天津血研所采用氨肽素治疗原发性血小板减少性紫癜(ITP)237例,成人183例有效率61.7%,小儿54例有效率66.7%。氨肽素是从猪蹄甲中提炼成,其中含有多种氨基酸、肽类和微量元素,无明显副作用。我院1985年后继续用氨肽素治疗15例ITP,其中6例进行了电镜观察。1 临床资料1.1 治疗对象 15例ITP均为慢性型,病程6月~20余年。年龄14~53岁,男7例,女8例。均有不同程度的皮肤、粘膜出血,女患者月经过多。实验室检查:血小板8.O×10~9/L~54.O×10~9/L,骨髓涂
From August 1980 to August 1982, 237 cases of idiopathic thrombocytopenic purpura (ITP) were treated with aminopeptin in our hospital, 23 hospitals in China and Tianjin Blood Institute. The effective rate of 183 cases in adults was 61.7%. Children 54 The effective rate of 66.7%. Aminpeptin is extracted from the trotters, which contains a variety of amino acids, peptides and trace elements, no significant side effects. After 1985, our hospital continue to use aminopeptin treatment of 15 cases of ITP, of which 6 cases were electron microscopy. 1 clinical data 1.1 treatment of 15 cases of ITP are chronic type, duration of 6 months to 20 years. Aged 14 to 53 years old, 7 males and 8 females. Have different degrees of skin, mucous membrane bleeding, women with menorrhagia. Laboratory tests: platelets 8.O × 10 ~ 9 / L ~ 54.O × 10 ~ 9 / L, bone marrow smear