Inhibitory leukocyte immunoglobulin-like receptors in cancer development

来源 :中国科学：生命科学英文版 | 被引量 : 0次 | 上传用户：liongliong533

【摘要】

：

Inhibitory leukocyte immunoglobulin-like receptors(LILRB1-5) signal through immunoreceptor tyrosine-based inhibitory motifs(ITIMs) in their intracellular domain

【作者】

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ZHANG FeiFei ZHENG JunKe KANG

【机构】

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HongqiaoInternationalInstituteofMedicine,FacultyofBasicMedicine,KeyLaboratoryofCellDifferentiationan

【出处】

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中国科学：生命科学英文版

【发表日期】

：

2015年12期

【关键词】

：

免疫球蛋白受体表达肿瘤细胞白细胞蛋白酪氨酸磷酸酶信号转导免疫细胞调节作用 immunoreceptor tyrosine-based inhibi

【基金项目】

：

supported b y the Na tional In stitu te o f Health（1R01CA172268）, the Leukemia＆Lymphoma Society（1024-14,TRP-6024-14）, the Robert A.Welch Foundation（I-1834）, the Cancer Prevention and Research Institut

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Inhibitory leukocyte immunoglobulin-like receptors(LILRB1-5) signal through immunoreceptor tyrosine-based inhibitory motifs(ITIMs) in their intracellular domains and recruit phosphatases protein tyrosine phosphatase, non-receptor type 6(PTPN6, SHP-1), pro

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Inhibitory leukocyte immunoglobulin-like receptors in cancer development

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