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目的 调查男女性别差异对阻塞性睡眠呼吸暂停的影响情况.方法 将275例阻塞性睡眠呼吸暂停(obstructive sleep apnea,OSA)病人分为男性组153例、女性组122例,观察两组的临床特征,对多导睡眠图各项目变化进行监测.结果 男性OSA病人主要发病年龄为45～65岁组,女性组发病年龄较均衡,两组超重或肥胖比例均较大.男性组OSA病人易于合并高血脂(83.7％),女性病人易于合并高血压(73.0％)与2型糖尿病(64.8％).男性组呼吸暂停低通气指数(apnea hypopnea index,AHI)以轻中度增加为主,女性组AHI中重度增加多于男性,差异有统计学意义(P＜0.01).结论 了解OSA临床特征的性别差异将有助于提高对OSA的识别和诊断,以选择更好的治疗方案,改善OSA病人的预后.“,”Objective To investigate the influence of sex difference on obstructive sleep apnea in men and women.Methods 275 patients with obstructive sleep apnea(OSA) were divided into 153 male groups and 122 female patients according to different genders.The clinical features of the two groups were observed,and the changes of polysomnography (PSG) items were monitored.Results The main onset age of OSA in male patients is 45 ～ 65 years,while the age of onset is more balanced in female group.The proportion of overweight or obesity is larger in two groups.OSA in male patients were prone to complicated with hyperlipidemia (83.7％),and women were prone to hypertension (73.0％) and type 2 diabetes mellitus (64.8％).The AHI of male group increased mild and moderate,and the AHIin female group increased more severe than that in male group,the difference was statistically significant (P ＜0.01).Conclusion It will help to improve the identification and diagnosis of OSA by understanding the gender differences in clinical characteristics of OSA and select better treatment options to improve the prognosis of patients with OSA.