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为评价近红外光谱测定技术(NIRS)对正常及围产期缺氧新生儿脑反应性功能的检测意义,本文检测了54例不同程度缺氧新生儿及33例正常新生儿安静状态下脑活动时氧合状态和听觉刺激后脑活动增强时氧合状态反应性变化。结果显示出正常新生儿稳态的脑功能活动及对刺激良好的反应状态;重度缺氧后72小时内脑反应性功能状态明显减弱,尤以生后24小时最差,与临床明显中枢神经系统症状及心血管系统损害相平行。提示NIRS可用于新生儿生理及病理状态下脑反应性功能的检测,能更早期、直接、敏感地反应脑损伤程度并估价预后。
In order to evaluate the significance of NIRS in the detection of cerebral reactivity in neonates with normal and perinatal hypoxia, we tested the brain activity in 54 hypoxic neonates and 33 normal neonates during quiescence Oxygenation state responsiveness at the time of oxygenation and brain activity increase after auditory stimulation. The results showed that normal neonatal steady-state brain function and stimulation of the state of good response; severe hypoxia within 72 hours after the brain reactive functional status significantly weakened, especially in 24 hours after birth, the worst, and clinically significant central nervous system Symptoms and cardiovascular system damage parallel. It is suggested that NIRS can be used to detect brain reactive function in neonatal physiology and pathology, reflect the degree of brain damage more early, directly and sensitively, and evaluate the prognosis.