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本研究采用先进的三维超声成像技术及多普勒技术对正常育龄妇女月经周期中心血管功能进行研究。结果：月经周期中ＨＲ、ＢＰ无变化；血清Ｅ２是周期性变化，排卵前达高峰。ＳＶ、ＣＯ、ＥＦ在排卵前期升高达峰值，显著高于月经期和黄体期；ＳＶＲ排卵前期最低，而Ｖｅｄ、Ｖｅｓ无变化。Ｖｍａｘ、Ａ、Ｅ在内源性Ｅ２高峰时明显加快，而Ｅ／Ａ比值无明显变化。结果提示：月经周期中随内源性Ｅ２的周期性变化，心脏功能也发生周期性变化。Ｅ２高峰时，心输出量、心搏量和射血分数达最高。外周阻力最低，心脏内血流速度加快。
In this study, advanced three-dimensional ultrasound imaging and Doppler techniques were used to study the cardiovascular function of menstrual cycle in normal women of childbearing age. Results: There was no change of HR and BP in the menstrual cycle. Serum E2 was periodic change and peaked before ovulation. SV, CO, EF increased in preovulatory peak, significantly higher than the menstrual period and luteal phase; SVR lowest ovulation, Ved, Ves no change. Vmax, A, E significantly increased at the peak of endogenous E2, while the E / A ratio did not change significantly. The results suggest that: With the cyclical changes of endogenous E2 in the menstrual cycle, cardiac function also changes cyclically. E2 peak, cardiac output, stroke volume and ejection fraction up to the highest. The lowest peripheral resistance, intracardiac blood flow speed.