内科非甲状腺疾病甲状腺激素变化及其临床意义

• 作 者: 冼苏 林碧霞 夏宁 黄瑞衡 韦敏怡
• 机 构: 广西医学院附属医院内分泌科,广西医学院附属医院内分泌科,广西医学院附属医院内分泌科,广西医学院附属医院内分泌科,广西医学院附属医院病理科,
• 出 处: 广西医学院学报
• 发表日期: 1991年04期
• 关键词: 非甲状腺疾病 甲状腺滤泡 甲状腺激素 甲状腺轴 血清 内科 腺上皮细胞 垂体 心衰 胶质

观察7种内科非甲状腺疾病193例患者血清垂体—甲状腺轴激素水平。结果:低T_3血症者占41.6％,高γT_3血症者占61.2％,低T_4血症占16.3％。病情越重,血清T_3的降低及γT_3升高越明显,同时伴血清T_4浓度的降低。低T_3、T_4血症持续并加重者,提示预后不良,病人多死亡;而治疗后低T_3、T_4血症有所改善者,病情则好转。对10例死亡病例进行尸解发现,处于低T_3、T_4血症的非甲状腺疾病患者,其甲状腺滤泡扩大,充满胶质,腺上皮细胞变扁平。

To observe the serum pituitary-thyroid axis hormone levels in 193 patients with non-thyroid diseases. Results: Low T 3 hyperlipidemia accounted for 41.6%, high γT_3 hyperlipidemia 61.2%, low T 4 hyperlipidemia 16.3%. Serious illness, serum T_3 decreased and γT_3 increased more significantly, accompanied by decreased serum T_4 concentration. Low T_3, T_4 hyperlipidemia continued and exacerbated, suggesting a poor prognosis, the patient more death; and treatment of low T_3, T_4 hyperlipidemia were improved, the condition is improved. The autopsy of 10 death cases found that in patients with non-thyroid disease with low T_3 and T_4 hyperlipidemia, the thyroid follicles expanded, filled with glia, and the glandular epithelial cells became flattened.