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本文通过78例临床资料的回顾性研究,确定Rh阴性妇女作羊膜穿刺而不予Rh免疫球蛋白时Rh因子致敏的危险性。作者对1972～1978年间78例Rh阴性妇女在妊娠中期为进行遗传病检查而作羊膜穿刺术的临床资料,包括过去分娩史,此次妊娠结局,羊膜穿刺后Rh免疫抗体滴度测定及有关新生儿情况作了回顾分析,结果是无致敏反应者49例(其中4例是在两次妊娠中均作了羊膜穿刺术),Rh因子致敏者3例,羊膜穿刺术后给予Rh因子免疫球蛋白治疗者2例。余为婴儿或父亲是Rh因子阴性,选择性流产以及既往有Rh因子致敏史者,本组病人均无自发性流产。
In this paper, a retrospective study of 78 cases of clinical data to determine the Rh-negative women as amniocentesis without Rh immunoglobulin Rh factor sensitization risk. The author of 78 cases of Rh-negative women from 1972 to 1978 in the second trimester of pregnancy for genetic testing for amniocentesis clinical data, including past history of delivery, the outcome of this pregnancy, amniocentesis Rh immune antibody titers and the relevant newborn Children were analyzed retrospectively, the result was no allergic reaction in 49 cases (of which 4 were in both pregnancies were made of amniocentesis), Rh factor sensitization in 3 cases, after amniocentesis given Rh factor immune 2 cases of globulin treatment. Yu as a baby or father is Rh-negative, selective abortion and previous history of Rh-allergen, this group of patients without spontaneous abortion.