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目的观察地诺前列酮栓剂(欣普贝生)用于足月引产的临床效果及安全性。方法56例足月妊娠单胎待产孕妇,无阴道分娩禁忌证,采用地诺前列酮栓一枚放置于阴道后引产。进行塞药前、塞药后12h宫颈Bishop评分记录临产时间、分娩方式、新生儿情况以及不良反应等。结果地诺前列酮栓促宫颈成熟的总有效率89.3%;临产时间(8.1±2.8)h;阴道分娩率82.1%。无不良反应;新生儿结局良好。结论地诺前列酮栓剂可以有效改善宫颈条件,诱发宫缩,提高阴道分娩成功率,对母、婴均无明显不良影响,可安全、有效地应用于足月引产。
Objective To observe the clinical efficacy and safety of dinoprostone suppository (Qin Pubei Sheng) for term labor induction. Methods 56 cases of single-term pregnant women with full-term pregnancy to be pregnant, vaginal birth contraindications, using droperidol suppository placed in the vagina after the induction of labor. Cervical medicine before and after the Cypriot medicine 12h cervical Bishop score recording of labor time, mode of delivery, neonatal conditions and adverse reactions. Results The total effective rate of dinoprostone suppository on cervical ripening was 89.3%; the duration of labor was (8.1 ± 2.8) h; the vaginal delivery rate was 82.1%. No adverse reactions; neonatal outcome is good. CONCLUSION: Dinoprostone suppository can effectively improve cervical conditions, induce uterine contractions and improve the success rate of vaginal delivery. It has no obvious adverse effects on both mother and infant and can be used safely and effectively in full-term induced labor.