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目的：探讨家兔接受不同的极低剂量γ射线全身照射后，对相继较大剂量照射所诱导的细胞遗传学损伤的抗性。方法：用６０Ｃｏ－γ射线对家兔进行慢性全身均匀照射，当累积剂量分别达到０．０５，０．１０，０．１５，０．２０、０．２５、０．３０Ｇｙ时，取静脉血，常规条件下培养，分别在淋巴细胞的Ｇ０期和Ｇ２期以１．５ＧｙＸ射线１次照射，制备染色体标本。结果：Ｇ０期和Ｇ２期受大剂量照射后，分别在０．１５Ｇｙ和０．２０Ｇｙ以上可诱导出明显的适应性反应（Ｐ＜０．０５），而在０．１０Ｇｙ和０．１５Ｇｙ以下则不能诱导出适应性反应。结论：本文为能诱导出适应性反应的Ｄ１剂量提供了最低阀值。
OBJECTIVE: To investigate the resistance of rabbits to cytogenetic damage induced by successive larger doses of radiation after being exposed to different very low doses of γ-rays. Methods: The whole body was irradiated with 60Co-γ-rays. When the cumulative doses reached 0.05, 0.10, 0.15, 0.20, 0.25 and 0.30Gy respectively, Under normal conditions, chromosomes were prepared by irradiating 1.5Gy X-ray once in G0 phase and G2 phase of lymphocytes, respectively. Results: At G0 phase and G2 phase, significant adaptive responses (P <0.05) were induced at 0.15Gy and 0.20Gy respectively after high dose irradiation, while at 0.10Gy and 0.15Gy Can not induce adaptive response. Conclusion: This article provides the lowest threshold for D1 dose to induce adaptive responses.