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目的:观察喜炎平注射液联合超声导入经皮给药治疗小儿轮状病毒肠炎的临床疗效。方法:治疗组125例:采用喜炎平注射液联合超声导入经皮给药。对照组127例:利巴韦林针静滴。共治疗婴幼儿轮状病毒肠炎252例,治疗期间观察患儿脱水情况、体温、大便次数及性状,并行大便镜检病毒。结果,治疗组总有效率100%,显著高于对照组(84.0%)(P<0.05),治疗组退热快,大便次数和性状恢复快,大便镜检病毒恢复阴性早,两组比较,差异有统计学意义(P<0.05)。结论:喜炎平注射液联合超声导入经皮给药治疗小儿轮状病毒肠炎疗效好,值得临床推广。
Objective: To observe the clinical effect of Xiyanping injection combined with ultrasound guided transdermal delivery in treatment of pediatric rotavirus enteritis. Methods: The treatment group of 125 cases: Xiyanping injection combined with ultrasound guided transdermal delivery. Control group of 127 cases: ribavirin needle intravenous infusion. A total of 252 cases of infantile rotavirus enteritis were treated during the treatment of children with dehydration, body temperature, stool frequency and traits, parallel stool virus. Results: The total effective rate was 100% in the treatment group, significantly higher than that in the control group (84.0%) (P <0.05). The treatment group had rapid fever, fast recovery of stool frequency and traits, The difference was statistically significant (P <0.05). Conclusion: Xiyanping injection combined with ultrasound guided transdermal delivery of pediatric rotavirus enteritis is effective and worthy of clinical promotion.