论文部分内容阅读
目的 了解 HBs Ag携带者补硒对 HBV转归的影响。方法 对 HBs Ag携带者 2 0 6 5例随机分为补硒组和对照组 ,连续服药观察 3年。2组随机抽检各 5 0 0例 HBV五项指标。结果 服药前补硒组与对照组无显著性差异 (P >0 .0 5 ) ,服药后 1年 ,补硒组 HBs Ag转阴率 10 .8% ,抗 - HBs阳性率为 5 .6 % ,两组均出现显著性差异 (P <0 .0 0 1) ;同时补硒组 HBs Ag转阴率显著高于对照组6 .4% (P <0 .0 0 5 ) ,抗 - HBs检测率补硒组亦显著高于对照组 1% (P <0 .0 0 1)。结论 补硒对改善HBV感染、促使 HBs Ag转阴与抗 - HBs的产生及预防肝癌的发生具有十分重要的临床意义。
Objective To understand the effect of supplementing selenium on HBsAg carriers. Methods A total of 2656 HBsAg carriers were randomly divided into selenium-supplemented group and control group. The patients were continuously treated for 3 years. Two groups randomly selected five hundred and fifty HBV markers. Results There was no significant difference between the selenium group and the control group before taking the drug (P> 0.05). One year after taking the drug, the negative rate of HBsAg in the selenium group was 10.8% and the positive rate of anti-HBs was 5.6% (P <0.01). At the same time, the negative rate of HBs Ag in selenium - supplemented group was significantly higher than that in control group (6.4%, P <0.05) Rates of selenium group was also significantly higher than the control group 1% (P <0. Conclusion Supplemental selenium has important clinical significance in improving HBV infection, promoting the production of HBsAg and anti - HBs and preventing the occurrence of liver cancer.