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众所周知无脾患者易发生暴发性败血症,且病情凶险,虽经积极抢救,病死率仍高达50％。病原菌主要是肺炎球菌,也有由流脑球菌和流感杆菌所致者,少数病人可发生细菌性脑膜炎。英国诺丁汉市大学医院自1974～1985年12年间共收治435例细菌性脑膜炎患者,其中5例在脾切除后发生6次脑膜炎,均为肺炎球菌所致。同期该院共行448例脾切除术。平均每75次脾切除术即可发生1次细菌性脑膜炎。该市有60万人口,12年来发生63例次肺炎球菌性脑膜炎,平均每1万人发生1例,
It is well known that patients with splenomegaly are prone to fulminant sepsis and are in dangerous condition. Despite active rescue, the case fatality rate is still as high as 50%. Pathogenic bacteria are mainly pneumococcal, but also by the meningitis and influenza caused by bacteria, a small number of patients can occur bacterial meningitis. Nottingham City University Hospital in the United Kingdom from 1974 to 1985, a total of 435 cases of bacterial meningitis were treated in patients, of which 5 cases occurred after splenectomy 6 meningitis, are due to pneumococcal. The same period the hospital a total of 448 cases of splenectomy. Bacterial meningitis occurs once every 75 splenectomies. The city has 600,000 inhabitants, 63 cases of pneumococcal meningitis in 12 years, an average of 1 case per 10,000 people,