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目的了解重庆地区健康人群维生素D(VitD)营养状况。方法用串联质谱分析仪检测送检人员血清25-羟维生素D[25(OH)VitD]水平,据此确定VitD营养状况。随机抽取重庆金域医学检验所从2012年1-8月的体检健康人员共3 875例,3～71岁。按年龄分为≤14岁儿童组(657例)、15～44岁青壮年组(3 019例)和≥45岁中老年组(199例)3组,采用SPSS 13.0统计软件进行数据分析。结果年龄≤14岁组的25(OH)VitD水平严重缺乏、缺乏、不足、正常、过量所占的比例分别为1.52%、19.03%、9.44%、70.02%和0%;15～44岁组水平缺乏、不足、正常、过量的比例分别为60.09%、27.59%、12.32%和0%;≥45岁组水平缺乏、不足、正常、过量的比例分别为84.92%、13.07%、2.01%和0%。15～44岁组和≥45岁组女性25(OH)VitD平均水平均较男性低,缺乏的女性人数较男性所占比例高,差异均有统计学意义(P<0.01),而≤14岁组男女间差异无统计学意义;≥45岁组与15～44岁组相比,25(OH)VitD平均水平随着年龄增加而降低,差异有统计学意义(P<0.01)。结论重庆地区人群VitD不同程度缺乏,女性缺乏所占比例较男性高,儿童有严重缺乏。
Objective To understand the nutritional status of Vitamin D in healthy population in Chongqing. Methods Serum 25-hydroxyvitamin D [25 (OH) VitD] was detected by tandem mass spectrometry analyzer to determine VitD nutritional status. A total of 3875 cases of health check-ups were conducted from January to August 2012 in Chongqing Jinyu Medical Laboratory, ranging from 3 to 71 years. They were divided into three groups according to their age: children ≤14 years old (657 cases), young adults aged 15-44 (3019 cases) and middle-aged and elderly patients ≥45 years old (199 cases). Data were analyzed by using SPSS 13.0 statistical software. Results The serum levels of 25 (OH) VitD in patients ≤14 years of age were severely deficient, lacking, deficient, normal and overdose were 1.52%, 19.03%, 9.44%, 70.02% and 0% The proportions of deficiency, deficiency, normal and overdose were 60.09%, 27.59%, 12.32% and 0% respectively. The levels of lacking, deficient, normal and overweight in the group of ≥45 years were 84.92%, 13.07%, 2.01% and 0% . The mean levels of 25 (OH) VitD in women aged 15-44 and ≥45 years were lower than those in men, and the proportion of women lacking was significantly higher than that of men (P <0.01) There was no significant difference between men and women in the group. The average level of 25 (OH) VitD in ≥45-year-old group was lower than that in the 15-44-year-old group with increasing age (P <0.01). Conclusion There is a lack of VitD in Chongqing population. The proportion of women lacking is higher than that of men and there is a serious lack of children.