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阿霉素是一种抗癌抗生素类药物,抗癌谱广。我院血液科近2年来应用国产阿霉素治疗恶性血液病97例,其结果显示:ANLL39例,缓解率为74.4%;ALL25例,缓解率88.0%;MM21例,缓解率85.7%;ML、CML-A、MH分别为6例、3例和2例,缓解率为66.7%、66.7%和50%;CLL1例获完全缓解,总缓解率达79.4%,取得了较好的疗效。用药期间仅见恶心、呕吐、脱发及白细胞下降等副反应,停药后可恢复,未发现明显的心、肝、肾等损害。
Adriamycin is an anti-cancer antibiotic drugs, broad spectrum of anti-cancer. Our hospital hematology in recent 2 years, 97 cases of domestic doxorubicin treatment of hematologic malignancies, the results showed: ANLL39 cases, the remission rate was 74.4%; ALL25 cases, the remission rate was 88.0%; MM21 cases, remission rate 85 .7%; ML, CML-A, MH were 6 cases, 3 cases and 2 cases, the remission rates were 66.7%, 66.7% and 50%; CLL1 patients were completely relieved, the total response rate was 79. 4%, achieved a good effect. During treatment only nausea, vomiting, hair loss and leukopenia and other side effects, withdrawal can be restored, no significant heart, liver, kidney damage.