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目前儿童广泛口服的脊髓灰质炎糖丸就是一个消化道黏膜免疫成功的例子。但在实践中,口服疫苗经过消化道时常受到消化液的降解,疫苗很容易被破坏,使消化道黏膜免疫方法的应用和推广受到限制。黏膜免疫是近几年来人们研究的热点内容,黏膜是与抗原接触的第一个部位,黏膜局部免疫和全身系统免疫对于防御病原体进入机体至关重要。随着分子生物学、细胞生物学和遗传学的渗透,现代免疫学深入到分子和基因
The current widespread oral polio pill for children is a case of successful digestive tract mucosal immunity. However, in practice, the oral vaccine is often degraded by digestive juice through the digestive tract, the vaccine is easily destroyed, and the application and promotion of the mucosal immunization method of the alimentary tract is limited. Mucosal immunity is one of the hot topics in recent years. Mucosal mucosa is the first site to contact with antigen. Local mucosal immunity and systemic immune system are very important for preventing pathogens from entering the body. With the infiltration of molecular biology, cell biology and genetics, modern immunology goes deep into molecules and genes