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慢性肾衰竭的病人有色素沉着,这可能是由于黑色素的关系。作者研究了28例慢性肾衰竭病人血浆β-黑色细胞刺激素(β-MSH),其中男16例,女12例,有7人每周用腹膜透析治疗(48小时/周),13人有规律的血液透析(3×6～8小时/周),8人没有用透析治疗。由每个病人取血测定免疫反应性β-MSH,在某些病人中也同时测定了血清肌酐。其中有21个病人测定了手背和背部的皮肤色素沉着。另外测定了25个正常人血浆β-MSH水平以作对照。慢性肾衰竭病人免疫反应性β-MSH大大增加,
Chronic renal failure patients have pigmentation, which may be due to melanin. The authors studied the plasma β-MSH in 28 patients with chronic renal failure, including 16 males and 12 females, of whom 7 were treated with peritoneal dialysis weekly (48 hours / week) and 13 with Regular hemodialysis (3 × 6 ~ 8 hours / week), 8 were not treated with dialysis. Immunoreactive β-MSH was determined by blood sampling in each patient, and serum creatinine was also measured in some patients. Twenty-one of these patients measured skin pigmentation on the back and back of their hands. In addition, 25 normal human plasma β-MSH levels were determined for comparison. Chronic renal failure patients with immunoreactive β-MSH greatly increased,