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胰腺癌是肿瘤治疗中的难题,外科手术切除是惟一存在潜在治愈可能的治疗方法,但只有少数病例能够进行手术切除,而且术后总体生存率很低。新辅助治疗逐渐被研究应用于胰腺癌,不仅有希望提高手术切除胰腺癌病例的生存期,而且有可能通过降低胰腺癌分期提高手术切除率。虽然已有研究证实新辅助化疗或放化疗对可切除胰腺癌的效果,但总体结果仍存在很大争议。
Pancreatic cancer is a difficult problem in cancer treatment. Surgical resection is the only possible treatment with potential cure. However, only a few cases can be surgically removed, and the overall postoperative survival rate is very low. Neoadjuvant therapy is gradually being studied for pancreatic cancer, not only hope to improve the survival of patients with pancreatic cancer resected, but also may improve the resection rate by reducing the pancreatic cancer staging. Although studies have confirmed the effect of neoadjuvant chemotherapy or radiotherapy and chemotherapy on resectable pancreatic cancer, the overall outcome remains controversial.