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目的：探讨烧伤后早期果胶强化要素膳对肠源性感染的防治效果。方法：以烧伤大鼠为模型，随机分２组，每组分别用要素膳（ＥＤ）或添加果胶的ＥＤ给予肠内营养７天。烧伤后，再用肠内营养支持７天，观察门静脉血（ＰＶＢ）细菌培养，肠系膜淋巴结（ＭＬＮ）细菌培养，血浆内毒素（ＬＰＳ），肠粘膜ＤＮＡ含量以及肠粘膜形态学等指标的变化。结果：添加果胶的ＥＤ能降低ＰＶＢ和ＭＬＮ的细菌易位率，降低ＬＰＳ的水平（Ｐ＜０．０５），减少粘膜ＤＮＡ的丢失（Ｐ＜０．０５），并有效地改善肠粘膜形态学变化。结论：果胶强化ＥＤ能够保护肠粘膜屏障，防治肠源性感染
Objective: To explore the prevention and treatment effect of early pectin fortified elements on gut-derived infection after burn. Methods: Burn rats were randomly divided into 2 groups. Each group received enteral nutrition for 7 days with ED or pectin. After burn, the patients were enrolled in enteral nutrition for 7 days. The changes of bacterial culture of PVB, bacterial culture of mesenteric lymph node (MLN), plasma endotoxin (LPS), intestinal mucosa DNA content and intestinal mucosa morphology were observed. Results: The addition of pectin ED reduced the bacterial translocation rate, decreased the LPS level (P <0.05), decreased the mucosal DNA loss (P <0.05), and effectively improved the intestinal mucosa morphology Learning changes. Conclusion: Pectin-enhanced ED can protect the intestinal mucosal barrier against enterogenous infection