N-Protection of amines using pyridinium 2,2,2-trifluoroacetate ionic liquid as an efficient and reus

• 作 者: Somaye Karimian Hassan Tajik
• 机 构: Department of Chemistry,Persian Gulf University,Department of Chemistry,University of Guilan,
• 出 处: Chinese Chemical Letters
• 发表日期: 2014年02期
• 关键词: amines reusable ionic Clean liquids hydrogenation aniline acetate silica hexane

A simple,green,and efficient method for the N-tert-butoxycarbonylation of amines by pyridinium 2,2,2-trifluoroacetate([Py][OTf]) as an efficient and reusable catalyst is reported.In general,electron donating groups on aryl group give rise to the higher yields than electron withdrawing groups.Clean reaction,short reaction times,high yields,reusability of catalyst,and easy preparation of it are some advantages of this work.

A simple, green, and efficient method for the N-tert-butoxycarbonylation of amines by pyridinium 2,2,2-trifluoroacetate ([Py] [OTf]) as an efficient and reusable catalyst is reported.In general, electron donating groups on aryl group give rise to the higher yields than electron withdrawing groups. Clean reaction, short reaction times, high yields, reusability of catalyst, and easy preparation of it are some advantages of this work.