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1991年3～8月,我们检测了各型病毒性肝炎住院患者的血β_2微球蛋白(β_2-MG)含量,并对其变化的临床意义进行了探讨。病例来源 本组共52例,均为住院确诊的患者.男37例,女15例。年龄16～71岁,平均38.7岁。其中急性肝炎(急肝)22例,慢性活动型肝炎(慢活肝)25例,重症肝炎(重肝)5例。52例中单纯抗-HAV IgM阳性者4例,乙型肝炎血清标志物(HBVM)阳性者37例(其中两项均阳性者3例),阴性者11例.另以健康成人21例做为正常对照,男16例,女5例,平均年龄27岁。方法 血β_2-MG采用RIA法检测,抗-HAVIgM和HBVM采用ELISA法检测。全部病例均做肝功能检测.
From March to August 1991, we examined the blood levels of β_2-MG in hospitalized patients with various types of viral hepatitis and explored its clinical significance. The source of this group of 52 patients, all patients diagnosed in hospital, 37 males and 15 females. Age 16 ~ 71 years old, average 38.7 years old. Among them, 22 cases of acute hepatitis (acute liver), 25 cases of chronic active hepatitis (slow living liver) and 5 cases of severe hepatitis (severe liver). Among the 52 cases, 4 were positive for anti-HAV IgM alone, 37 were positive for hepatitis B virus (HBVM) positive (3 of them were positive in both) and 11 were negative, and 21 were healthy adults Normal control, 16 males and 5 females, mean age 27 years old. Methods Blood β_2-MG was detected by RIA method. Anti-HAVIgM and HBVM were detected by ELISA. All cases were done liver function tests.