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目的:观察天麻素联合倍他司汀治疗老年梅尼埃病临床疗效。方法:将老年梅尼埃病患者96例按双盲法随机分为2组各48例。单一组服用倍他司汀,治疗组在此基础上加用天麻素,观察患者症状改善效果、症状改善用时,同时对用药期间2组不良反应情况进行统计比较。结果:治疗组在眩晕消失、其他症状消失、总治疗时间上较单一组患者症状改善用时少(P<0.05)。用药后症状改善有效率治疗组为95.8%,单一组为85.4%,2组比较,差异有统计学意义(P<0.05)。服药后不良反应发生率治疗组8.3%,单一组16.7%,2组不良反应情况比较,差异有统计学意义(P<0.05)。结论:天麻素联合倍他司汀治疗老年梅尼埃病疗效确切,不良反应小。
Objective: To observe the clinical efficacy of gastrodin combined with Betatine in the treatment of Meniere’s disease in elderly. Methods: Ninety-six elderly patients with Meniere’s disease were randomly divided into two groups (n = 48) according to the double-blind method. A single group taking betahistine, the treatment group on the basis of the use of gastrodin, to observe the symptoms of patients to improve the effectiveness of symptoms with time, while the two groups during the adverse drug reactions statistical comparison. Results: The treatment group disappeared after dizziness, other symptoms disappeared, and the total treatment time was less than that of the single group (P <0.05). After treatment, the effective rate of symptom improvement was 95.8% in the treatment group and 85.4% in the single group. There was significant difference between the two groups (P <0.05). The incidence of adverse reactions after treatment in the treatment group 8.3%, single group 16.7%, two groups of adverse reactions, the difference was statistically significant (P <0.05). Conclusion: Gastrodin combined with Betatine treatment of senile Meniere’s disease has definite curative effect and small adverse reaction.