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目的研究妊娠期糖尿病孕妇的血脂变化。方法选择正常孕妇4O例(对照组),妊娠期糖尿病孕妇75例,测定空腹静脉血清胆固醇(TC)、甘油三酯(TG)、高密度脂蛋白(HDL-C)、低密度脂蛋白(LDL-C)、载脂蛋白A(ApoA)、载脂蛋白B(ApoB)、脂蛋白a(Lp(a))水平。结果妊娠期糖尿病组与对照组相比,TC、TG、LDL-C、ApoB测定值升高(P<0.05),HDL-C、ApoA测定值降低(P<0.05),Lp(a)无统计学意义(P>0.05)。结论血脂代谢异常可能在妊娠期糖尿病的发病中起一定作用。
Objective To study the changes of serum lipids in pregnant women with gestational diabetes mellitus. Methods Forty cases of normal pregnant women (control group) and 75 pregnant women with gestational diabetes mellitus were enrolled in this study. Fasting venous blood cholesterol (TC), triglyceride (TG), high density lipoprotein (HDL-C), low density lipoprotein -C), apolipoprotein A (ApoA), apolipoprotein B (ApoB), lipoprotein a (Lp (a)). Results Compared with the control group, the levels of TC, TG, LDL-C and ApoB in gestational diabetes mellitus group were significantly increased (P <0.05), HDL-C and ApoA levels were lower (P <0.05) Significance (P> 0.05). Conclusion Abnormal lipid metabolism may play a role in the pathogenesis of gestational diabetes.