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目的:探讨胸腔内注入草酸铂与香菇多糖治疗恶性胸腔积液的效果。方法:对34例恶性胸腔积液患者采用胸腔内置入中心静脉导管,抽液后随机分成A、B两组,A组胸腔内注入草酸铂加香菇多糖;B组胸腔内注入草酸铂。结果:治疗恶性胸腔积液A组疗效(CR+PR)86.4%(19/22);B组疗效(CR+PR)58.3%(7/12)。结论:胸腔内置管注入草酸铂与香菇多糖治疗恶性胸腔积液的疗效优于单用草酸铂,且不良反应轻微。
Objective: To investigate the effect of intrapleural infusion of oxaliplatin and lentinan on malignant pleural effusion. Methods: Thirty-four patients with malignant pleural effusion were treated with central venous catheter in the thoracic cavity. After being drained, the patients were randomly divided into A and B groups. A group was injected oxaliplatin plus lentinan intrapleurally; Results: The treatment of malignant pleural effusion in group A (CR + PR) 86.4% (19/22); group B (CR + PR) 58.3% (7/12). CONCLUSION: Intrathoracic injection of oxaliplatin and lentinan in the treatment of malignant pleural effusion is superior to oxaliplatin alone and the adverse reactions are mild.