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目的探讨早发型重度子痫前期对孕产妇及围生儿结局的影响,旨在提高对早发型重度子痫前期的认识。方法选取早发型重度子痫前期患者71例为早发型组,晚发型重度子痫前期患者269例为晚发型组,比较两组一般情况、并发症及围生儿结局。结果早发型重度子痫前期与晚发型重度子痫前期相比,胎盘早剥、肝功能异常、低蛋白血症方面及围生儿结局(出生体质量、胎儿生长受限、围生儿死亡率)差异均有统计学意义(P<0.05或P<0.01)。结论早发型重度子痫前期并发症多,围生儿结局不良率高,应及时识别,及时处理。
Objective To investigate the effect of early onset severe preeclampsia on the outcomes of pregnant women and perinatal infants and to improve the understanding of early onset severe preeclampsia. Methods 71 cases of early-onset severe preeclampsia were selected as early-onset group and 269 cases of late-onset severe preeclampsia as late-onset group. The general conditions, complications and perinatal outcome were compared between the two groups. Results Compared with late onset severe preeclampsia in early-onset severe preeclampsia, there were no significant differences in placental abruption, abnormal liver function, hypoproteinemia and perinatal outcome (birth weight, fetal growth restriction, perinatal mortality ) Differences were statistically significant (P <0.05 or P <0.01). Conclusion There are many complications of early onset severe preeclampsia and high incidence of perinatal uninfected children. It should be promptly identified and treated promptly.