Effects of Nerve Growth Factor Expression on Perineural Invasion and Worse Prognosis in Early-Stage

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To the Editor:Several kinds of malignant tumors show perineural invasion (PNI),which can cause locoregional recurrence and reduce the likelihood of survival after surgery.Our previous study has shown that PNI in cervical cancer is associated with other pathology risk features,and other studies have shown that it is a predictor of poor prognosis.[1-3] These findings highlight the importance of clarifying the molecular mechanism of PNI.
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