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目的:探讨中西医结合治疗慢性浅表性胃窦炎的临床疗效,为临床治疗方案的制定提供参考。方法:选取在医院就诊的慢性浅表性胃窦炎患者128例,随机分为观察组和对照组各64例。对照组采用西医常规治疗方案进行治疗,观察组在对照组治疗方案的基础上,加用中药平胃散加减口服治疗。治疗2周后对比两组患者的临床疗效、治疗前后的中医症状积分评分结果和血清胃泌素水平的变化情况。结果:观察组的总有效率为90.63%,对照组的总有效率为76.56%,观察组的总有效率显著高于对照组(均P<0.05);两组患者治疗后的症状积分评分结果均显著低于治疗前(均P<0.05);观察组治疗后胃痛的评分为(4.71±1.36)分,胃胀的评分为(4.41±1.71)分,反酸的评分为(5.58±2.41)分,嗳气的评分为(4.61±1.96)分,纳差的评分为(3.86±1.24)分,均显著低于对照组(均P<0.05);两组患者治疗后血清胃泌素水平均显著高于对照组(均P<0.05);观察组治疗后的血清胃泌素水平为(98.68±7.31)mg/L,显著高于对照组(P<0.05)。结论:中西医结合治疗方案有助于慢性浅表性胃窦炎患者胃黏膜的修复,促进胃功能的恢复,显著改善患者的临床症状,提高临床治疗效果。
Objective: To explore the clinical curative effect of treating chronic superficial antral gastritis with integrated traditional Chinese and western medicine, and to provide a reference for the formulation of clinical treatment. Methods: A total of 128 patients with chronic superficial gastritis who were hospitalized were randomly divided into observation group (64 cases) and control group (64 cases). The control group was treated with conventional treatment of Western medicine, the observation group in the control group based on the treatment program, plus traditional Chinese medicine Pingwei San oral treatment. After 2 weeks of treatment, the clinical curative effect of the two groups of patients was compared, the score of TCM symptom score before and after treatment and the change of serum gastrin level were compared. Results: The total effective rate was 90.63% in the observation group and 76.56% in the control group, and the total effective rate in the observation group was significantly higher than that in the control group (all P <0.05). The symptom score score (4.71 ± 1.36), bloating score (4.41 ± 1.71) and acid reflux score (5.58 ± 2.41) in the observation group after treatment (4.61 ± 1.96) points and the score of anorexia (3.86 ± 1.24) points were significantly lower than those of the control group (all P <0.05). Serum gastrin levels were significantly higher in both groups after treatment (P <0.05). The level of serum gastrin in the observation group was (98.68 ± 7.31) mg / L, which was significantly higher than that in the control group (P <0.05). Conclusion: The combination of traditional Chinese medicine and western medicine treatment is helpful to the repair of gastric mucosa in patients with chronic superficial gastritis, promote the recovery of gastric function, significantly improve the clinical symptoms and improve the clinical curative effect.