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目的分析浙江省成年人群血脂水平及与生活方式的相关性,为血脂异常防治提供科学依据。方法采用多阶段分层整群随机抽样的方法,按经济发展水平及类型将浙江省90个县(市、区)分成2类城市和3类农村共5类地区,每类地区抽取3个县/区,每个县区随机抽取4个街道/乡镇,每个街道/乡镇随机抽取3个村/居委会,共调查15个样本县(市、区)7 222户样本家庭中年龄18周岁及以上的常住人口(近半年内在该家庭户居住6个月以上的居民),纳入分析的有效样本量为17 437人,对其进行问卷调查和血脂检测,分析吸烟、饮酒行为和体力活动对血脂的影响。结果调查对象血脂异常患病率为48.00%(8 369/17 437),其中高甘油三酯血症的患病率为13.02%(2 271/17 437),高胆固醇血症的患病率为2.53%(442/17 437),低高密度脂蛋白血症的患病率为41.49%(7 234/17 437)。多因素logistic回归分析结果显示,甘油三酯(TG)与BMI和重度吸烟(≥20支/d)呈正相关;总胆固醇(TC)与体质指数(BMI)、适量身体锻炼(150~420min/周)、职业活动强度、吸烟(<20支/d)有关;高密度脂蛋白胆固醇(HDL-C)与BMI、职业活动强度、吸烟、饮酒有关。结论控烟限酒、适量体力活动、积极控制体重等生活方式的转变是控制血脂水平的重要方法。
Objective To analyze the relationship between serum lipids and lifestyle in Zhejiang adults and to provide a scientific basis for the prevention and treatment of dyslipidemia. Methods A multistage stratified cluster random sampling method was used to divide 90 counties (cities and districts) of Zhejiang Province into 5 types of areas in 2 types of cities and 3 types of rural areas according to the level of economic development and types. Three types of counties / District, each county / district randomly selected 4 streets / townships, towns and villages in each street randomly selected 3 village / neighborhood, a total of 15 sample counties (cities, districts) 7 222 sample households aged 18 years and above Of the resident population (residents living in the household for more than 6 months in the past six months), the effective sample size for inclusion in the analysis was 17,437. Questionnaires and blood lipid tests were conducted to analyze smoking, drinking behaviors and physical activity on blood lipids influences. Results The prevalence of dyslipidemia was 48.00% (8 369/17 437). The prevalence of hypertriglyceridemia was 13.02% (2771/17 437). The prevalence of hypercholesterolemia was 2.53% (442/17 437). The prevalence of low-density lipoproteinemia was 41.49% (7 234/17 437). Multivariate logistic regression analysis showed that triglyceride (TG) was positively correlated with BMI and severe smoking (≥20 cigarettes per day); total cholesterol (TC) and body mass index (BMI), moderate physical exercise (150-420min / ), Intensity of occupational activity and smoking (<20 cigarettes per day). High-density lipoprotein cholesterol (HDL-C) was related to BMI, occupational activity intensity, smoking and drinking. Conclusions The change of life style such as alcohol restriction, adequate physical activity and active body weight control are important methods to control blood lipid level.