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目的了解系统的团体药物管理训练对康复期精神分裂症患者家庭负担的影响。方法 2011年12月-2013年12月将101例康复期精神分裂症患者随机分为干预组(56例)和对照组是(45例),干预组进行药物管理训练,对照组只进行简单随访,为期6个月。采用阴性症状和阳性症状量表(PANSS)评估患者的精神症状,采用精神病患者家庭负担会谈量表(FBS)评定精神病患者给家庭带来的负担。结果干预组较对照组在PANSS阳性症状(t=2.692,P=0.008)、阴性症状(t=2.729,P=0.008)、一般病理(t=3.231,P=0.002)和整体精神病性症状(t=3.870,P<0.001)的改善方面都优于对照组,且患者精神病性症状的改善程度与FBS家庭负担改善程度呈正相关(r=0.44,P<0.001)。结论系统的药物管理训练能提高患者的治疗依从性,改善治疗效果从而减轻患者和家庭的负担。
Objectives To understand the impact of systematic group drug management training on family burdens in convalescent patients with schizophrenia. Methods From December 2011 to December 2013, 101 patients with convalescent congenital schizophrenia were randomly divided into intervention group (n = 56) and control group (n = 45). The intervention group was given drug management training and the control group received only simple follow-up For a period of 6 months. The psychiatric symptoms were assessed using the Negative Symptom and Positive Symptom Scale (PANSS) and the Family Burden Mental Disorder Scale (FBS) was used to assess the burden on families of psychiatric patients. Results Compared with the control group, the positive rates of PANSS positive (t = 2.692, P = 0.008), negative (t = 2.729, P = 0.008), general pathology (t = 3.231, P = 0.002) and overall psychotic symptoms = 3.870, P <0.001) were better than the control group, and the improvement of psychotic symptoms was positively correlated with the improvement of family burdens of FBS (r = 0.44, P <0.001). Conclusions Systemic drug management training can improve patients’ compliance with treatment and improve the curative effect so as to reduce the burden on patients and their families.