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本文报导我院1979～1982年门诊所见胃复安引起急性肌张力障碍28例。男17例,女11例。年龄5～45岁。儿童及青年占61%。剂量为20～40mg/日,多在服药后1～3天突然出现头颈僵硬、偏斜或后仰,张口伸舌或流涎,言语及吞咽障碍、脸部不随意动作或眼上翻,少数出现肢体及躯干扭转或四肢强直性痉挛和角弓反张。呈阵发性,历时1～5分钟,缓解1～3分钟再发。本组病例均以肌注东茛菪硷0.3mg消除症状,多数在注射后15分钟症状好转,少数好转速度较慢者给予安坦2mg一日三次口服,二天后停药。胃复安与吩噻嗪类药物同样能引起锥体外系反
This article reports from 1979 to 1982 in our clinic see metoclopramide caused acute dystonia in 28 cases. 17 males and 11 females. Age 5 to 45 years old. Children and youth make up 61%. Dosage of 20 ~ 40mg / day, and more in 1 to 3 days after taking the sudden onset of head and neck stiffness, skewed or reclined, mouth stretch or salivation, speech and swallowing disorders, facial involuntary movements or eye up, a few appear Torsion of limbs and torso or limbs with tonic spasms and antinodal spine. Was paroxysmal, which lasted 1 to 5 minutes, ease 1 to 3 minutes and then send. This group of patients were intramuscular injection of scopolamine 0.3mg eliminate symptoms, most of the symptoms after 15 minutes of injection improved, a few slower turn to give Antan 2mg three times a day orally, two days after the withdrawal. Metoclopramide and phenothiazine drugs can cause extrapyramidal anti-retrograde