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以药理方法筛选分离出花生衣中止血有效成分可能为醌类化合物,通过分离出的活性组分作为相对标准品对宁血糖浆进行鉴别试验和含量测定,并初步制订该制剂质控标准应定在0.41~0.51mg/100g范围内。同时应控制花生衣原料含有效成分应在0.6%左右。实验证明药厂生产宁血糖浆的工艺是合理的。
The pharmacological method for screening and separation of the active ingredients in the peanut coating may be an anthraquinone compound, and the isolated active component is used as a relative standard to perform a differential test and content determination on the Ning glucose syrup, and a preliminary formulation of the quality control standard for the preparation shall be made. In the range of 0.41 to 0.51 mg/100g. At the same time, it should be controlled that the active ingredient in the raw material of peanuts’ clothing should be about 0.6%. Experiments have proved that the process used by the pharmaceutical factory to produce Ning glucose syrup is reasonable.