论文部分内容阅读
目的观察三蠲促凋法联合化疗治疗中晚期大肠癌患者的临床疗效及其对生活质量、生存率的影响。方法将60例晚期大肠癌患者随机分为治疗组30例和对照组30例。治疗组采用三蠲促凋法联合化疗进行治疗,对照组单纯用化疗。结果治疗组中医临床疗效、生活质量、免疫功能、3年累计生存率及中位生存期均优于对照组,化疗不良反应发生率低于对照组,差异有显著性(P<0.05)。实体瘤近期疗效,获益率治疗组90.00%,对照组72.22%(P<0.05)。结论三蠲促凋法联合化疗治疗中晚期大肠癌在抑制肿瘤病灶,改善临床症状,增强免疫功能,提高生活质量,延长生存期方面都具有较好的作用。
Objective To observe the clinical efficacy and its effect on the quality of life and the survival rate of patients with advanced colorectal cancer treated with the combination of chemotherapy with triadimefon and apoptosis. Methods Sixty patients with advanced colorectal cancer were randomly divided into treatment group (30 cases) and control group (30 cases). The treatment group was treated with the combination of triadimefon method and chemotherapy and the control group with chemotherapy alone. Results The clinical curative effect, quality of life, immune function, 3-year cumulative survival rate and median survival time were all better in the treatment group than those in the control group. The incidence of adverse reactions was lower in the treatment group than in the control group (P <0.05). The short-term curative effect of solid tumor was 90.00% in the treatment group and 72.22% in the control group (P <0.05). Conclusion The combination of chemotherapy with triadimefon in the treatment of advanced colorectal cancer has a good effect in inhibiting tumor lesions, improving clinical symptoms, enhancing immune function, improving quality of life and prolonging survival.