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目的:观察清热活血合剂治疗头颈部肿瘤放射性口干症的临床疗效。方法:选取2013年3月~2014年8月在我科行放疗的头颈部恶性肿瘤患者共60例,随机分为实验组和对照组,两组均行全程IMRT放射治疗及放射性口干症的基础治疗,实验组在上述基础上加用清热活血合剂,比较两组放疗后口干程度及唾液分泌量。结果:放疗结束后,实验组口干程度明显低于对照组,差异具有统计学意义(P=0.048);实验组唾液分泌量明显高于对照组,差异具有统计学意义(P<0.05)。结论:运用清热活血合剂可以有效的减轻放射性口干症,值得在肿瘤放疗并发症的防治中推广运用。
Objective: To observe the clinical efficacy of “Qingrehuoxue Mixture” in the treatment of radiation-induced dry mouth and head and neck cancer. Methods: A total of 60 patients with head and neck cancer undergoing radiotherapy from March 2013 to August 2014 in our hospital were randomly divided into experimental group and control group. Both groups underwent full IMRT and radiation-induced xerophthalmia Of the basic treatment, the experimental group on the basis of the above plus heat Huoxue Mixture, the two groups were compared after salvage dry mouth and salivary secretion. Results: After the end of radiotherapy, the degree of dry mouth of the experimental group was significantly lower than that of the control group (P = 0.048). The salivary secretion of the experimental group was significantly higher than that of the control group (P <0.05). Conclusion: The application of Qingrehuoxue Mixture can effectively relieve radiation-induced xerostomia and is worth promoting in the prevention and treatment of the complications of radiotherapy.