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藤黄科(Guttiferae)植物被认为是具有HIV抑制活性的天然产物的重要资源,曾从该科胡桐属Calophyllum的C.langiferumvar.austrocoriaceum中分离得到(+)-calanolideA(),它是一个有专属性的HIV-1逆转录酶抑制剂,现在正进行期临床试验。另一新的camboginol类异戊烯化二苯甲酮抗HIV物
The genus Guttiferae is considered to be an important resource of natural products with HIV-inhibitory activity. It was isolated from C. langiferum var. astrocoriaceum of the family Calanuphyllum genus (+)-calanolideA (). Specific HIV-1 reverse transcriptase inhibitors are now undergoing clinical trials. Another new camboginol prenylated benzophenone anti-HIV drug