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报告1例并发Corynebacterium jeikeium(JK)棒状杆菌感染的皮肤利什曼病病例。患者男,49岁。双前臂红色丘疹、结节、渗液、溃疡、结痂伴疼痛7个月余。患者发病前于阿富汗工作,有白蛉叮咬史。体格检查:系统查体无异常。皮肤科检查:双前臂肿胀明显,可见散在分布、蚕豆至乒乓球大、红色至暗紫红色斑块、结节,质中,活动可,略浸润,表面可见黄色渗液、结痂,部分皮疹中央可见浅溃疡,溃疡基底未见明显脓性分泌物,触痛(+)。实验室及辅助检查:皮损组织细菌培养可见JK棒状杆菌。皮损组织病理检查:表皮缺损并有溃疡、不规则增生,真皮内可见弥漫淋巴细胞、组织细胞、浆细胞浸润,组织细胞胞质内及周围可见很多圆形或卵圆形嗜碱性小体。诊断:皮肤利什曼病;皮肤JK棒状杆菌感染。治疗予头孢呋辛及葡萄糖酸锑钠治疗,皮损痊愈。
One case of cutaneous leishmaniasis was reported with Corynebacterium jeikeium (JK) Corynebacterium infection. Male patient, 49 years old. Double forearm red papules, nodules, exudate, ulcers, scabs with pain more than 7 months. Before the onset of the disease in Afghanistan, there is a history of white bites. Physical examination: no abnormal physical examination. Dermatology examination: double forearm swelling obvious, scattered distribution, broad beans to ping-pong, red to dark purple patches, nodules, quality, activity can be slightly infiltration of the surface visible yellow exudate, crusting, partial rash Central visible shallow ulcer, ulcer base no obvious purulent secretions, tenderness (+). Laboratory and laboratory examinations: Bacterial cultures of skin lesions showed JK coryneform bacteria. Skin lesions and pathological examination: epidermal defects and ulceration, irregular proliferation, diffuse lymphocytes seen in the dermis, tissue cells, plasma cell infiltration, the cytoplasm and around the organization can see a lot of round or oval basophilic body . Diagnosis: Cutaneous Leishmaniasis; Skin JK Corynebacterium Infection. Treatment to cefuroxime and sodium gluconate treatment, skin lesions healed.