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美国芝加哥消息:基因转移疗法治疗某些遗传性疾病即将问世。洛杉矶加利福尼亚大学的研究者Martin Cline将新的基因试验转移给人——两名患β-地中海贫血的病人,一名在以色列,另一名在意大利,其他的试验也已开始。绝大多数医学及分子遗传学家预言,某些免疫缺陷疾病(可能也有α-1-抗胰蛋白酶缺陷及某些尿素环酶病)将是基因疗法新的首选适应症。两名病人通过肝脏及骨髓移植疗法,可获得成功,但需有良好的组织相容性配型。
Chicago, United States: Gene Delivery Therapeutics Certain genetic diseases are coming soon. Martin Cline, a researcher at the University of California, Los Angeles, relocated the new genetic test to two people with beta-thalassemia, one in Israel and the other in Italy. Other trials have begun. Most medical and molecular geneticists predict some of the immunodeficiency diseases (and possibly alpha-1-antitrypsin deficiency and some urease cyclo-enzyme disease) will be the new indications of choice for gene therapy. Two patients were successfully treated with liver and bone marrow transplantation but required good histocompatibility.